PS-OCT Reveals Scleral Fiber Changes in High Myopia and DSM
This study explores scleral abnormalities in highly myopic eyes using polarization-sensitive optical coherence tomography (PS-OCT). PS-OCT can visualize scleral collagen fibers, providing insights into pathologic myopia, including dome-shaped macula (DSM). Researchers examined 89 highly myopic eyes from 72 patients, comparing those with and without DSM.
Findings revealed distinct differences in scleral fibers between the two groups. In eyes without DSM, the inner scleral layer showed low-density, radially oriented fibers, while the outer layer had high-density, vertically oriented fibers. However, in eyes with DSM, inner scleral fibers were aggregated and thickened, while outer scleral fibers were compressed but not thickened.
These observations suggest that PS-OCT can enhance the understanding of scleral pathologies in high myopia. By identifying specific fiber patterns associated with DSM, this imaging technique may aid in developing targeted treatments to address these abnormalities early, potentially preventing further damage to the eye's neural tissues. The study highlights the importance of recognizing scleral fiber orientation and density in managing and treating pathologic myopia effectively.
